Prostaglandins act like hormones, causing blood vessels and smooth muscles to constrict, resulting in cramping and pain. Researchers have found prostaglandin levels are higher and uterine contractions are stronger and more frequent in women with menstrual pain than women who have little or no pain, according to American Association of Family Physicians.

Eating inflammatory foods only adds to the discomfort, studies have found. Highly processed and high-sugar foods and fatty, greasy foods are common culprits — a 2018 study found college students who ate more snacks had more pain during their periods.

Another 2018 study of Spanish college students found women who drank cola and ate meat were more likely to suffer pain during their cycle than women who ate more vegetables and fruits. In fact, a 2020 study found women who ate fewer than two servings of fruit a day were more likely to suffer pain during their menstrual cycle.

Part of the problem is an imbalance between omega-3 and omega-6 fatty acids, Sannoh found. Omega-3 fatty acids — found in foods such as salmon, tuna, sardines, oysters, walnuts, chia and flaxseeds — are anti-inflammatory. Studies have linked them to a reduction in risk for many chronic diseases triggered by inflammation.

Omega-6 fatty acids keep skin, hair and bones healthy and help regulate metabolism, in addition to their role in the reproductive system. But too many of these fatty acids can cause inflammation when the body ultimately breaks them down into arachidonic acid, which lowers the body’s pain threshold.

“From my research, I found out that people with diets high in omega-6 fatty acids, especifically those derived from animal-based products, have a higher presence of arachidonic acid in the body, which increases the amount of pro-inflammatory prostaglandins that help the uterus contract,” Sannoh said.

“When you have a diet that balances omega-3 and omega-6 fatty acids, and you decrease the amount of inflammatory foods that you ingest, that will decrease the painful menstrual experience,” she added.

Two separate studies from 2011 and 2012 revealed women who took omega-3 fatty acid supplements reduced the intensity of menstrual discomfort enough to lower their use of ibuprofen for pain relief. And a 1996 study found a highly significant relationship between omega-3 fatty acids and milder menstrual symptoms in teens.

Other solutions

Changing your diet is not the only way to fight menstrual pain. Nonsteroidal anti-inflammatory drugs, or NSAIDs, reduce the production of prostaglandins, which is why they are a mainstay of treatment for cramps, Christmas said.

However, these pain medications also have side effects. According to a 2015 Cochrane Library review of evidence, NSAIDs are linked to bloating, diarrhea, dizziness, indigestion, headaches, heartburn, high blood pressure, nausea, vomiting and on rare occasions, raised liver enzymes.

Certain oral birth control pills also lower the production of prostaglandins in the uterine lining, which then reduces both blood flow and cramping. Doses of less than 35 micrograms were “effective and should be the preparation of choice,” according to a 2009 Cochrane Library review.

There’s an added benefit to adopting an anti-inflammatory lifestyle, Christmas said.

“These diets are also associated with less high blood pressure, less cardiovascular disease, less diabetes, less arthritic issues, decreased morbidity and mortality, especially after menopause,” Christmas said.

“So if you can get people who are young to eat better, exercise, and live a healthier lifestyle, they’re going fare better as they age.”